Search results for "Hepatic cirrhosis"

showing 3 items of 3 documents

Antidiabetic Drugs in NAFLD: The Accomplishment of Two Goals at Once?

2018

Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common cause of chronic liver disease in Western countries, accounting for 20–30% of general population and reaching a prevalence of 55% in patients with type 2 diabetes mellitus (T2DM). Insulin resistance plays a key role in pathogenic mechanisms of NAFLD. Many drugs have been tested but no medications have yet been approved. Antidiabetic drugs could have a role in the progression reduction of the disease. The aim of this review is to summarize evidence on efficacy and safety of antidiabetic drugs in patients with NAFLD. Metformin, a biguanide, is the most frequently used drug in the treatment of T2DM. To date 15 randomized controlled t…

3003medicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentlcsh:Medicinelcsh:RS1-441Pharmaceutical Sciencehepatic cirrhosis030209 endocrinology & metabolismReviewChronic liver diseaseGastroenterologylcsh:Pharmacy and materia medica03 medical and health sciences0302 clinical medicineInsulin resistanceInternal medicineDiabetes mellitusDrug DiscoverymedicineBiguanidebusiness.industryLiraglutideInsulinlcsh:RFatty liverThiazolidinedionenutritional and metabolic diseasesnon-alcoholic fatty liver diseaseLiraglutidemedicine.diseaseMetforminMetforminHepatic cirrhosiMolecular Medicine030211 gastroenterology & hepatologyThiazolidinedionesnon-alcoholic steatohepatitisbusinessNon-alcoholic steatohepatitimedicine.drugPharmaceuticals (Basel, Switzerland)
researchProduct

Prevalence of apical periodontitis and frequency of root canal treatments in liver transplant candidates

2013

Aim: The purpose of this study was to investigate the prevalence of apical periodontitis (AP) and endodontic treatment in liver transplant candidates and control healthy subjects. Material and Methods: A descriptive cross-sectional study. Forty two liver transplant candidates (LTC) (study group) and 42 control subjects. Digital panoramic radiographs where used. Periapical status was scored according to the periapical index (PAI). Results were analysed statistically using the Chi-squared test and logistic regression. Results: Radiographic signs of AP in one or more teeth was found in 79% of patients in the study group and in 50% of control subjects (p = 0.008; OR = 3.7; C. I. 95% = 1.4 - 9.5…

Malemedicine.medical_specialtyOral healthRoot-canal treatmentCross-sectional studyRoot canalmedicine.medical_treatmentDentistryOdontologíaLiver transplantationLogistic regressionEndodonticsLiver diseaseApical periodontitisPrevalencemedicineHumansGeneral DentistryPeriodontitisPeriapical periodontitisbusiness.industryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in Dentistrymedicine.diseaseEndodonticsCiencias de la saludLiver TransplantationRoot Canal TherapyCross-Sectional Studiesmedicine.anatomical_structureHepatic cirrhosisOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASResearch-ArticleFemaleSurgerybusinessLiver diseasePeriapical PeriodontitisMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Focal cortical damage parallels cognitive impairment in minimal hepatic encephalopathy

2012

Little attention has been paid to cortical integrity in patients with minimal hepatic encephalopathy (MHE), although cognitive functions affected in early stages of liver disease are mainly allocated in different neocortical structures. Here we used cortical surface-based analysis techniques to investigate if patterns of cortical thinning accompany the mildest form of HE. To aim this goal, cortical thickness obtained from high-resolution 31 magnetic resonance imaging (MRI) was measured in patients with no MHE (NMHE), MHE, and healthy controls. Further correlation analyses were performed to examine whether scores in the critical flicker frequency (CFF) test, and blood ammonia levels accounte…

Malemedicine.medical_specialtyPathologyCognitive NeuroscienceMinimal hepatic encephalopathyPrecuneusFlicker fusion thresholdNeuropsychological TestsCortical thicknessLiver diseaseInternal medicineImage Interpretation Computer-AssistedmedicineHumansHepatic encephalopathyTemporal cortexCerebral Cortexmedicine.diagnostic_testMagnetic resonance imagingCognitionMiddle Agedmedicine.diseaseEarly diagnosisMagnetic Resonance ImagingCalcarine sulcusmedicine.anatomical_structureEarly DiagnosisCognitive impairmentNeurologyHepatic cirrhosisHepatic EncephalopathyCardiologyFemalePsychologyCognition Disordershuman activities
researchProduct